主要科研成果与奖励(主持项目、获奖、著作、代表性论文) 主持项目: 1. 2014-2017,国家自然科学基金面上项目:大肠埃希氏菌S-腺苷高半胱氨酸核苷酶的作用机制及其作为抗菌药物靶点的探究; 2. 2011-2013,国家自然科学基金面上项目:YabC的甲基转移酶功能及其在大肠杆菌细胞分裂过程中的作用。 代表性论文: 1. Weiwei Hao, Yanhua Li, Qiuli Shan, Tian Han, Wencheng Li, Sheng He, Kongkai Zhu, Yumei Li, Xiaojun Tan,Jinsong Gu*, Characterization of human S-adenosyl-homocysteine hydrolase in vitro and identification of its potential inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 2017, 32(1): 1209–1215 2. Tian Han, Yanhua Li, Qiuli Shan, Wenjing Liang, Weiwei Hao, Yumei Li, Xiaojun Tan,Jinsong Gu*, Characterization of S-adenosylhomocysteine /Methylthioadenosine nucleosidase on secretion of AI-2 and biofilm formation of Escherichia coli. Microbial Pathogenesis. 2017, 108(7): 8–84 |